What is Zofran?
Zofran is an anti-nausea medication which can be administered 30 minutes before the start of emetogenic chemotherapy, with a subsequent dose 8 hours after the first dose. It can be given to adults and pediatric patients age 4 and older, although the pediatric dosage is lower. Ondansetron, marketed under the name Zofran, belongs to the class of medications called 5-HT3 receptor antagonists. Zofran reduces vomiting and nausea by reducing the effects of a naturally-occurring chemical in the body called serotonin. The medication Ondansetron is currently sold under several generic brands and has been approved by the FDA. Drugs which may be equivalent to Zofran ODT are sold by BARR, Glenmark Generics, Mylan, Ranbaxy, Sandoz, Sun Pharm Industries, and Teva. Other less reputable pharmacies may also sell illegal generic versions of Zofran ODT. Medical experts warn about buying certain medications because they can be counterfeit and potentially unsafe.